Neurotransmitter discharge and postsynaptic rise times
نویسندگان
چکیده
منابع مشابه
Neurotransmitter Receptors in the Postsynaptic Neuron
Communication between adjacent neurons in the central nervous system occurs at specialized regions of the nerve cells termed the synapse. It is mediated by themovement of chemical mediators or neurotransmitters across a small gap that exists between the nerve cells. When a neuron is activated, it releases molecules of neurotransmitter from synaptic vesicles localized in the presynaptic terminal...
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The human brain is made up of an extensive network of neurons that communicate by forming specialized connections called synapses. The amount, location, and dynamic turnover of synaptic proteins, including neurotransmitter receptors and synaptic scaffolding molecules, are under complex regulation and play a crucial role in synaptic connectivity and plasticity, as well as in higher brain functio...
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Presynaptic and postsynaptic differentiation occurs at axodendritic contacts between CNS neurons. Synaptic adhesion mediated by synaptic cell adhesion molecule (SynCAM) and beta-neurexins/neuroligins triggers presynaptic differentiation. The signals that trigger postsynaptic differentiation are, however, unknown. Here we report that beta-neurexin expressed in nonneuronal cells induced postsynap...
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The precise times of occurrence of individual pre- and postsynaptic action potentials are known to play a key role in the modification of synaptic efficacy. Based on stimulation protocols of two synaptically connected neurons, we infer an algorithm that reproduces the experimental data by modifying the probability of vesicle discharge as a function of the relative timing of spikes in the pre- a...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 1996
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(96)79769-2